Simpson became the first running back in NFL history to rush for over 2000 yards, eclipsing the mark by three yards. In the process he broke the season rushing yards record held by Jim Brown of 1863 yards. In the final week of the season Simpson rushed for 200 yards in a win over the Jets. After a loss to the eventual Super Bowl champion Miami Dolphins in week 10 to drop the team to 5-5 the Bills rattled off four straight wins to end the season on the back of OJ Simpson. Until Matt Ryan matched the feat last year Ferguson was the only rookie QB to start immediately and win four of his first five starts.

Coming off his first thousand-yard season, OJ Simpson uncorked in the first game rushing for a record 250 yards and 2 touchdowns in the season opener against the Patriots. The offensive changes took place almost immediately. They were so named because they provided the electricity for the 'Juice', O.J. The 'Electric Company' was the nickname for the offensive line featuring OG Reggie McKenzie, OT Dave Foley, C Mike Montler, OG Joe DeLamielleure and OT Donnie Green as well as fullback Jim Braxton, tight end Paul Seymour. The Electric Company led the Bills to a dramatic turnaround on the field. Simpson, and the team had its first winning record since 1966. Rookie Joe Ferguson became their new quarterback, the rushing offense took center stage behind O.J. In 1973 the Bills moved into their new digs in Orchard Park but that wasn't the only major change that took place. The team also selected linebackers John Skorupan in the sixth and Mervin Krakau in the 14th round. The Bills also replaced underachieving quarterback Dennis Shaw by selecting Joe Ferguson in the third round. They traded wideout Marlin Briscoe to the Dolphins for Miami's first round pick and selected eventual Hall of Fame guard Joe DeLamielleure.

In the first round the Bills selected tight end Paul Seymour seventh overall. Much like they had done in the 1961 draft, the Bills would select several cornerstones of the franchise in the 1973 draft. Prior to the 1973 season the Bills moved into Rich Stadium and One Bills Drive became the new address in Orchard Park as the home base for the team. Ultimately, a new stadium was built in Orchard Park and in 1972 Rich Products signed a 25-year, $1M deal to name the new field Rich Stadium. Because of the dilapidated state of the stadium Ralph WIlson briefly considered moving the team to Seattle. The league mandated 50,000 seats minimum in a stadium and the Rockpile held less than 47,000. While acceptable to AFL standards, the War Memorial in downtown Buffalo was being outclassed in the NFL. 9-5 record, Second of five in AFC East, Fifth of thirteen in AFC, Ninth-t of 26 in NFL

1973 buffalo bills roster